Randomized trial · Post hoc biomarker analysis
DO-HEALTH
2.9–3.8 months
Less biological aging on selected clocks over 3 years, compared with no omega-3 treatment.
- Who was studied
- 777 Swiss adults aged 70 or older, within the larger randomized trial.
- What changed
- Omega-3 was associated with slower change on selected DNA-methylation clocks. The combined interventions had an additive effect on PhenoAge.
- Limits
- Results varied by clock. This was a post hoc analysis of a relatively healthy subgroup, with two measurement time points. A longer lifespan was not established.