Aging is a tractable engineering problem.
We focus on the boring, repeatable, measurable parts of aging biology. We do not chase miracles. We track the seven mechanisms with the strongest current human data and pre-register our members for every qualifying cohort in the partner network.
Senolytic clearance
Senescent cells secrete an inflammatory cocktail (the SASP) that drives age-related disease. We pre-register members for the leading senolytic cohorts in the network, pulse-dosed dasatinib + quercetin (Helion Longevity Network), navitoclax pulse senolytic (Aevum Reprogramming), and the Mayo, Northwestern, and University of Colorado fisetin trials.
Cellular reprogramming
Partial expression of OSK Yamanaka factors resets epigenetic age without dedifferentiating tissue. Members are pre-registered for the OSK Partial Reprogramming first-in-human cohort at Aevum Reprogramming as soon as it opens recruitment in their tier.
Mitochondrial repair
Declining NAD+ availability and impaired mitophagy underlie metabolic frailty. The network includes NAD+ precursor cohorts (NR, NMN, MIB-725), MitoQ vascular trials at Colorado, and the Stealth elamipretide programs, your dashboard surfaces every cohort you qualify for.
Immune rejuvenation
Thymic involution drives most of immune aging. The Thymic Regeneration TRIIM-X cohort and IL-7 Thymic Augmentation Pilot (both at Intervene Immune) anchor the immune track, alongside the BCG vaccination follow-up at Radboud University Medical Center.
Plasma fractionation
The biology of young plasma is in the proteins, not the volume. Members are pre-registered for the Young Plasma Fractionation (E5) Pilot at Aevum Reprogramming and the GDF11 Systemic Rejuvenation Pilot at Elevian.
Metabolic & GLP-class
The cardiometabolic effects of titrated GLP-1 in non-diabetic adults rival the most ambitious longevity drugs. Metabolic is the largest active arm in the network, semaglutide, tirzepatide, AKG, and ketone-ester cohorts across Mayo Clinic, Northstar Metabolic, Ponce de Leon Health, and dozens of academic sites.
Cryopreservation
For the part of the bet that depends on outliving aging research itself: standby coordination, neuro and whole-body preservation through Tomorrow Bio's Charter Membership program, surfaced as a tier-gated enrollment alongside the rest of your stack.
Your tier decides your queue position.
See which active trials you'd qualify for and the partner labs running them.